According to the Doo race manuals, you should lose about 10 mph of top speed. The theoretical top speed of the 25/44 gear ratio is 116.1 mph, and for the 23/44 it is 106.9 mph. I would guess you'll be around 100 mph top speed if you were at about 105-110 before.
You should also run a 2 link shorter chain. Stock should be a 74 link chain, and the race manual says to use a 72 link chain. I have no idea if the adjuster can compensate for it (I would think that it would, but you'll be bending the chain more, so you'll lose some power there..)
You may also have to add some weight to your pins to keep your top speed rpm's down. (mine seems OK, I just dropped 1 tooth on my top sprocket, and went down 1position on my TRA clickers, but didn't have the chance to get going really fast yet).